Substrate specificity of protein kinase C inhibitors

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Substrate specificity of protein kinase C inhibitors.

In the August issue of TiPS, Epand and Lester analysed the effect of the physicochemical properties of the membrane on protein kinase C activity. In addition to those substrates discussed that require the presence of Ca2+ and phospholipids, other substrates can be phosphorylated in the absence of these activators. It is possible that this differential substrate requirement could be exploited ph...

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Specificity of the high affinity interaction of protein kinase C with a physiological substrate, myristoylated alanine-rich protein kinase C substrate.

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ژورنال

عنوان ژورنال: Trends in Pharmacological Sciences

سال: 1990

ISSN: 0165-6147

DOI: 10.1016/0165-6147(90)90136-v